Partial pressure of ammonia versus ammonia in hepatic encephalopathy.

  title={Partial pressure of ammonia versus ammonia in hepatic encephalopathy.},
  author={Ludwig Kramer and Barbara Tribl and Alexandra Gendo and Christian Zauner and Barbara Taback Schneider and P Ferenci and Christian Madl},
  volume={31 1},
Ammonia is considered the major pathogenetic factor of cerebral dysfunction in hepatic failure. The correlation between total plasma ammonia and the severity of hepatic encephalopathy (HE), however, is variable. Because ammonia that is present in gaseous form readily enters the brain, the correlation with the grade of HE of the pH-dependent partial pressure of gaseous ammonia (pNH(3)) could be better than that of total arterial ammonia levels. To test this hypothesis, 56 cirrhotic patients with… CONTINUE READING
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