Partial phenotypic suppression of a peroxisome-deficient animal cell mutant treated with aminoglycoside G418.

@article{Allen1992PartialPS,
  title={Partial phenotypic suppression of a peroxisome-deficient animal cell mutant treated with aminoglycoside G418.},
  author={Leanne Allen and Christian R. H. Raetz},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 19},
  pages={13191-9}
}
Certain enzymes normally associated with peroxisomes, such as the dihydroxyacetone phosphate (DHAP) acyltransferase involved in plasmalogen biosynthesis, are present at low levels in peroxisome-deficient mutants of Chinese hamster ovary (CHO) cells. We now show that the aminoglycoside G418 increases the residual DHAP acyltransferase in mutant ZR-82 by 60… CONTINUE READING