Partial penetrance facilitates developmental evolution in bacteria

@article{Eldar2009PartialPF,
  title={Partial penetrance facilitates developmental evolution in bacteria},
  author={A. Eldar and V. Chary and Panagiotis Xenopoulos and Michelle E. Fontes and O. Los{\'o}n and J. Dworkin and P. Piggot and M. Elowitz},
  journal={Nature},
  year={2009},
  volume={460},
  pages={510 - 514}
}
Development normally occurs similarly in all individuals within an isogenic population, but mutations often affect the fates of individual organisms differently. This phenomenon, known as partial penetrance, has been observed in diverse developmental systems. However, it remains unclear how the underlying genetic network specifies the set of possible alternative fates and how the relative frequencies of these fates evolve. Here we identify a stochastic cell fate determination process that… Expand
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