Partial off-loading of longitudinal tension induces arterial tortuosity.

@article{Jackson2005PartialOO,
  title={Partial off-loading of longitudinal tension induces arterial tortuosity.},
  author={Zane Steven Jackson and Dorota Dajnowiec and Avrum I. Gotlieb and Brian Lowell Langille},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2005},
  volume={25 5},
  pages={
          957-62
        }
}
OBJECTIVES Arterial tortuosity is a frequent manifestation of vascular disease and collateral vessel growth, but its causes are poorly understood. This study was designed to assess the relationship between the development of tortuosity and the mechanical forces that are imposed on arterial tissue. METHODS AND RESULTS Axial strain in rabbit carotid arteries was reduced from 62+/-2% to 33+/-2% by implanting an interposition graft, prepared from the contralateral carotid, at the downstream end… CONTINUE READING

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