Partial delipidation improves the T-cell antigenicity of hepatitis B virus surface antigen.

Abstract

Hepatitis B virus surface antigen (HBsAg) is a complex macromolecular particle composed of glycoproteins and lipids. The latter, representing 25% of the particle mass, are of host origin and determine the solubility, stability, and, indirectly, B-cell immunogenicity of HBsAg. HBsAg is a T-cell-dependent immunogen that does not elicit a detectable humoral… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.