Partial agonist effect influences the CTL response to a heterologous dengue virus serotype.

Abstract

Activation of dengue serotype-cross-reactive memory CTL during secondary dengue virus (DV) infection is thought to be important in the pathogenesis of dengue hemorrhagic fever. To model this effect, we studied the CTL responses to DV types 2 (D2V) and 3 (D3V) in PBMC from an individual previously infected with D3V. DV-specific CD8+ CTL from this donor… (More)

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Cite this paper

@article{Zivn1999PartialAE, title={Partial agonist effect influences the CTL response to a heterologous dengue virus serotype.}, author={Jaroslav Zivn{\'y} and Matthew DeFronzo and William Jarry and John Stuart Jameson and John Cruz and F. A. Ennis and Alan Rothman}, journal={Journal of immunology}, year={1999}, volume={163 5}, pages={2754-60} }