Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.

@article{Kim2014ParthenolideEI,
  title={Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.},
  author={S L Kim and S R Lee and Kieu Thi Thu Trang and Seong Hun Kim and In Hee Kim and Seung Ok Lee and Dae Ghon Kim and Sang Wook Kim},
  journal={International journal of molecular medicine},
  year={2014},
  volume={33 5},
  pages={1261-7}
}
Parthenolide (PT) is responsible for the bioactivities of feverfew (Tanacetum parthenium). Apart from its potent anti-inflammatory effects, this compound has been reported to induce apoptosis in various cancer cells. However, little is known about its role in the process of tumor angiogenesis. In the present study, we investigated the effects and potential… CONTINUE READING