Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro

@article{Lesiak2010ParthenolideAS,
  title={Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro},
  author={K. Lesiak and K. Koprowska and Izabela Zalesna and D. Nejc and M. Duechler and M. Czyz},
  journal={Melanoma Research},
  year={2010},
  volume={20},
  pages={21-34}
}
  • K. Lesiak, K. Koprowska, +3 authors M. Czyz
  • Published 2010
  • Biology, Medicine
  • Melanoma Research
  • Metastatic melanoma is a highly life-threatening disease. The lack of response to radiotherapy and chemotherapy highlights the critical need for novel treatments. Parthenolide, an active component of feverfew (Tanacetum parthenium), inhibits proliferation and kills various cancer cells mainly by inducing apoptosis. The aim of the study was to examine anticancer effects of parthenolide in melanoma cells in vitro. The cytotoxicity of parthenolide was tested in melanoma cell lines and melanocytes… CONTINUE READING
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