Parthenogenetic activation of pig oocytes with calcium ionophore and the block to sperm penetration after activation.

@article{Wang1998ParthenogeneticAO,
  title={Parthenogenetic activation of pig oocytes with calcium ionophore and the block to sperm penetration after activation.},
  author={Wen-Yan Wang and Zolt{\'a}n Mach{\'a}ty and Lalantha R. Abeydeera and Randall S Prather and Billy N. Day},
  journal={Biology of reproduction},
  year={1998},
  volume={58 6},
  pages={
          1357-66
        }
}
  • Wen-Yan Wang, Zoltán Macháty, +2 authors Billy N. Day
  • Published in Biology of reproduction 1998
  • Biology, Medicine
  • Calcium ionophore A23187 can parthenogenetically activate oocytes in many animals. The present study was designed to analyze functionally the mechanism of A23187 activation of pig oocytes matured in vitro. In experiment 1, effects of the concentration of A23187 on intracellular calcium transients, cortical granule (CG) exocytosis, nuclear activation, and zona reaction, which was determined by zona hardening and sperm penetrability, were examined. Cumulus-free oocytes were exposed to 0-100… CONTINUE READING

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