Paroxysmal muscle weakness - the familial periodic paralyses

  title={Paroxysmal muscle weakness - the familial periodic paralyses},
  author={Karin Jurkat-Rott and Frank Lehmann-Horn},
  journal={Journal of Neurology},
The familial periodic paralyses (PP) were commonly considered to be benign diseases since frequency and severity of the paralytic attacks decrease in adulthood. However, with increasing age, a third of the patients develop permanent weakness and muscle degeneration with fatty replacement. Another complication, cardiac arrhythmia, can result from the dyskalemia during paralytic attacks. The familial PP are typical dominant ion channelopathies: the function of the mutant muscular channel is… CONTINUE READING


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Chapter 46: Nondystrophic myotonias and periodic paralyses. In: Engel AG, Franzini-Armstrong C (ed) Myology

  • F Lehmann-Horn, R Rüdel, K Jurkat-Rott
  • 2004
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Chapter 46 : Nondystrophic myotonias and periodic paralyses

  • F Lehmann-Horn, R Rüdel, K Jurkat-Rott
  • 2004

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