Paroxysmal Sympathetic Hyperactivity after Severe Brain Injury

@article{Lump2014ParoxysmalSH,
  title={Paroxysmal Sympathetic Hyperactivity after Severe Brain Injury},
  author={Devon Lump and Megan T. Moyer},
  journal={Current Neurology and Neuroscience Reports},
  year={2014},
  volume={14},
  pages={1-7}
}
Paroxysmal sympathetic hyperactivity (PSH) is characterized by the rapid onset and paroxysmal cycling of agitation and dystonia in association with autonomic symptoms. These symptoms may include the following: tachycardia, hypertension, tachypnea, fever, pupil dilation, decreased level of consciousness, diaphoresis, and ventilator dyssynchrony. In a critically ill patient, these are all nonspecific symptoms that may reflect impending sepsis, seizure, or a number of other complications. This can… Expand
Paroxysmal Sympathetic Hyperactivity.
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TLDR
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Paroxysmal sympathetic hyperactivity: An entity to keep in mind.
TLDR
The excitation-inhibition model is the theory that best explains the different aspects of this condition, including the response to treatment with the available drugs, and the key therapeutic references are the early recognition of the disorder, avoiding secondary injuries and the triggering of paroxysms. Expand
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Early recognition and adequate treatment of paroxysmal sympathetic hyperactivity is important to avoid prolongation of the patient’s stay in the intensive care unit and to enable recovering patients to participate without restrictions in rehabilitation therapy. Expand
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The goals of this study were to describe the clinical associations and radiological findings of PSH, its incidence, and features in subjects with severe TBI in the intensive care unit (ICU), and to investigate the potential role of increased intracranial pressure in the pathogenesis ofPSH. Expand
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