Paroxetine serum concentrations in depressed patients and response to treatment.


INTRODUCTION There is no established relationship between the serum concentration of selective serotonin reuptake inhibitors (SSRIs) and clinical response in depressed patients. METHODS We analyzed paroxetine concentrations in serum of 46 depressed patients during treatment with a fixed dosage of 40 mg paroxetine. RESULTS After 5 weeks 29 patients… (More)


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