Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

Abstract

Paroxetine, a selective serotonin reuptake inhibitor for counteracting depression, has been recently suggested as having a role in prevention of dopaminergic neuronal degeneration in substantia nigra, a hallmark of Parkinson’s disease (PD). The pathogenesis of this type of neurological disorders often involves the activation of microglia and associated… (More)
DOI: 10.1186/1742-2094-11-47

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