Paroxetine: an update of its use in psychiatric disorders in adults.

  title={Paroxetine: an update of its use in psychiatric disorders in adults.},
  author={A. Wagstaff and S. Cheer and A. Matheson and D. Ormrod and K. Goa},
  volume={62 4},
  • A. Wagstaff, S. Cheer, +2 authors K. Goa
  • Published 2002
  • Medicine
  • Drugs
  • Paroxetine is a selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activity. In 6- to 24-week well designed trials, oral paroxetine 10 to 50 mg/day was significantly more effective than placebo, at least as effective as tricyclic antidepressants (TCAs) and as effective as other SSRIs and other antidepressants in the treatment of major depressive disorder. Relapse or recurrence over 1 year after the initial response was significantly lower with paroxetine 10 to 50… CONTINUE READING
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