Parkinsonism induced by solvent abuse

  title={Parkinsonism induced by solvent abuse},
  author={R.J. Uitti and Barry Snow and Hitoshi Shinotoh and François J. G. Vingerhoets and Margo Hayward and Stanley A. Hashimoto and John Richmond and Sanford P. Markey and Carol J. Markey and Donald B. Calne},
  journal={Annals of Neurology},
We report the first description of a patient with parkinsonism induced by solvent abuse. Our patient developed parkinsonism acutely, following heavy abuse of lacquer thinner. Her clinical deficits wee indistinguishable from idiopathic parkinsonism (Parkinson's disease) and she responded to levodopa. Parkinsonism has persisted for more than 3 months. Brain computed tomography was normal. Positron emission tomographic studies showed normal fluorodopa uptake and reduced raclopride binding… 

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