Parkinsonism in cirrhosis: pathogenesis and current therapeutic options

@article{Butterworth2012ParkinsonismIC,
  title={Parkinsonism in cirrhosis: pathogenesis and current therapeutic options},
  author={Roger F. Butterworth},
  journal={Metabolic Brain Disease},
  year={2012},
  volume={28},
  pages={261-267}
}
Acquired hepatolenticular degeneration, also known as “Parkinsonism in cirrhosis” is characterized by extrapyramidal symptoms including hypokinesia, dystonia and rigidity that are rapidly progressive and may be independent of the severity of cognitive dysfunction. Magnetic resonance imaging reveals T1-weighted hyperintense signals in both globus pallidus and substantia nigra. Estimates of the prevalence of Parkinsonism in cirrhosis have been reported as high as 21 %. The cause of Parkinsonism… CONTINUE READING
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