Parkinsonism, pyramidal signs, polyneuropathy, and cognitive decline after long-term occupational solvent exposure

@article{Hageman1999ParkinsonismPS,
  title={Parkinsonism, pyramidal signs, polyneuropathy, and cognitive decline after long-term occupational solvent exposure},
  author={Gerard Hageman and J. A. F. van der Hoek and M. S. E. van Hout and Gert van der Laan and Ernst N. H. Jansen Steur and Wieger I. de Bruin and Karl Herholz},
  journal={Journal of Neurology},
  year={1999},
  volume={246},
  pages={198-206}
}
It is well known that exposure to manganese, solvents, or carbon monoxide in an occupational setting may lead to central nervous system damage and parkinsonism. The most important solvents in this respect are methanol, toluene, carbon disulfide, and n-hexane. We describe three patients who had been exposed to various solvents for more than 20 years (25, 34, and 46 years). They presented with parkinsonism, pyramidal signs, mild cognitive decline, and unresponsiveness to levodopa. Two patients… CONTINUE READING
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Neurobehavioral effects of long - term exposure to xylene and mixed organic solvents in shipyard spray painters

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Neurobehavioral effects of long-term exposure to xylene and mixed organic solvents in shipyard

  • MWMM Ruyten, J Hooisma, JT Brons, CEP Habets, HH Emmen, H Muyser
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