Parkinson risk in idiopathic REM sleep behavior disorder: preparing for neuroprotective trials.

@article{Postuma2015ParkinsonRI,
  title={Parkinson risk in idiopathic REM sleep behavior disorder: preparing for neuroprotective trials.},
  author={Ronald B. Postuma and J F Gagnon and Josie-Anne Bertrand and Daphn{\'e} G{\'e}nier Marchand and Jacques Y. Montplaisir},
  journal={Neurology},
  year={2015},
  volume={84 11},
  pages={1104-13}
}
OBJECTIVE To precisely delineate clinical risk factors for conversion from idiopathic REM sleep behavior disorder (RBD) to Parkinson disease, dementia with Lewy bodies, and multiple system atrophy, in order to enable practical planning and stratification of neuroprotective trials against neurodegenerative synucleinopathy. METHODS In a 10-year prospective cohort, we tested prodromal Parkinson disease markers in 89 patients with idiopathic RBD. With Kaplan-Meier analysis, we calculated risk of… CONTINUE READING
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Cognitive impairment and slowing of waking EEG in RBD patients

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