Parkinson disease

@article{Poewe2017ParkinsonD,
  title={Parkinson disease},
  author={Werner Poewe and Klaus Seppi and Caroline M. Tanner and Glenda M. Halliday and Patrik Brundin and Jens Volkmann and Anette E Schrag and Anthony E. Lang},
  journal={Nature Reviews Disease Primers},
  year={2017},
  volume={3}
}
Parkinson disease is the second-most common neurodegenerative disorder that affects 2–3% of the population ≥65 years of age. Neuronal loss in the substantia nigra, which causes striatal dopamine deficiency, and intracellular inclusions containing aggregates of α-synuclein are the neuropathological hallmarks of Parkinson disease. Multiple other cell types throughout the central and peripheral autonomic nervous system are also involved, probably from early disease onwards. Although clinical… 

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  • J. JankovicE. Tan
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...

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