Parkinson disease

  title={Parkinson disease},
  author={Werner Poewe and Klaus Seppi and Caroline M. Tanner and Glenda M Halliday and Patrik Brundin and Jens Volkmann and A Schrag and Anthony E Lang},
  journal={Nature Reviews Disease Primers},
Parkinson disease is the second-most common neurodegenerative disorder that affects 2–3% of the population ≥65 years of age. Neuronal loss in the substantia nigra, which causes striatal dopamine deficiency, and intracellular inclusions containing aggregates of α-synuclein are the neuropathological hallmarks of Parkinson disease. Multiple other cell types… CONTINUE READING