Parkinson disease: How reliable are prodromal indicators of Parkinson disease?

Abstract

The failure of putative disease-modifying treatments to alter the course of neurodegenerative disorders has, in part, been blamed on the failure to intervene sufficiently early. As a consequence, identification of risk factors and detection of the earliest signs of pathological damage are now academic priorities in conditions such as Parkinson disease (PD… (More)
DOI: 10.1038/nrneurol.2014.235

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