Parkinson's disease

  title={Parkinson's disease},
  author={Ali Samii and John G. Nutt and Bruce R. Ransom},
  journal={The Lancet},
Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals. Symptoms of Parkinson's disease respond in varying degrees to drugs, and surgery offers hope for patients no longer adequately controlled in this manner. The high prevalence of the disease, and important advances in its management, mean that… Expand
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