Parkinson's disease and dementia: clinical and neurochemical correlations.

  title={Parkinson's disease and dementia: clinical and neurochemical correlations.},
  author={M M Strittmatter and Hinrich Cramer},
  volume={3 5},
In 38 old aged parkinsonian patients, two major subgroups could be established: one with predominant akinesia, rigidity, postural instability and accompanying cognitive impairment with intellectual deterioration correlated with duration of disease but not with age of onset and another with predominant tremor and relatively intact intellectual functions. The mean somatostatin-like immunoreactivity (SLI) level in the cerebrospinal fluid (CSF) was significantly lower in parkinsonian patients (21.4… CONTINUE READING


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