Parkinson's at risk syndrome: can Parkinson's disease be predicted?

  title={Parkinson's at risk syndrome: can Parkinson's disease be predicted?},
  author={Matthew B. Stern and Andrew D. Siderowf},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={25 Suppl 1},
The treatment of Parkinson's disease (PD) has revolved around pharmacologic interventions that primarily treat the cardinal (dopaminergic) manifestations of tremor, rigidity, and bradykinesia; yet, we now know that the pathology of PD is widespread, accounting for more disabling symptoms such as cognitive impairment, autonomic problems, and postural instability. Further, attempts at modifying PD may be hampered as much by the imperfection of therapeutic interventions as by the extent of… CONTINUE READING
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