Parkin-mediated ubiquitination regulates phospholipase C-γ1

Abstract

Mutations in parkin cause autosomal recessive forms of Parkinson's disease (PD), with an early age of onset and similar pathological phenotype to the idiopathic disease. Parkin has been identified as an E3 ubiquitin ligase that mediates different types of ubiquitination, which has made the search for substrates an intriguing possibility to identify… (More)
DOI: 10.1111/j.1582-4934.2008.00443.x

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Cite this paper

@inproceedings{Dehvari2009ParkinmediatedUR, title={Parkin-mediated ubiquitination regulates phospholipase C-γ1}, author={Nodi Dehvari and Anna Sandebring and Amilcar Flores-Morales and Laura Dara Mateos and Yin-Choy Chuan and Matthew S. Goldberg and Mark R Cookson and Richard F. Cowburn and Angel Cedazo-M{\'i}nguez}, booktitle={Journal of cellular and molecular medicine}, year={2009} }