Parkia javanica Extract Induces Apoptosis in S-180 Cells via the Intrinsic Pathway of Apoptosis

  title={Parkia javanica Extract Induces Apoptosis in S-180 Cells via the Intrinsic Pathway of Apoptosis},
  author={Kartick Patra and S. Jana and A. Sarkar and Subrata Karmakar and J. Jana and Mradu Gupta and Gopeswar Mukherjee and U. C. De and D. P. Mandal and Shamee Bhattacharjee},
  journal={Nutrition and Cancer},
  pages={689 - 707}
  • Kartick Patra, S. Jana, +7 authors Shamee Bhattacharjee
  • Published 2016
  • Biology, Medicine
  • Nutrition and Cancer
  • ABSTRACT Parkia javanica is a leguminous tree, various parts of which are used as food and folklore medicine by the ethnic groups of northeastern India. The present study investigates the in vitro and in vivo anticancer effect of aqueous methanol extract of P. javanica fruit (PJE). HPLC analysis was done to establish the fingerprint chromatogram of PJE and its in vitro radical scavenging activity was measured. PJE caused significant cytotoxicity in sarcoma-180 (S-180), A549, AGS, and MDA-MB435S… CONTINUE READING
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