Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications

@article{Su2006ParietalEyePC,
  title={Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications},
  author={C Y Su and Dong Gen Luo and Akihisa Terakita and Yoshinori Shichida and Hsi Wen Liao and Manija A. Kazmi and Thomas P. Sakmar and King-Wai Yau},
  journal={Science},
  year={2006},
  volume={311},
  pages={1617 - 1621}
}
The parietal-eye photoreceptor is unique because it has two antagonistic light signaling pathways in the same cell—a hyperpolarizing pathway maximally sensitive to blue light and a depolarizing pathway maximally sensitive to green light. Here, we report the molecular components of these two pathways. We found two opsins in the same cell: the blue-sensitive pinopsin and a previously unidentified green-sensitive opsin, which we name parietopsin. Signaling components included gustducin-α and Gαo… 
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116 Citations
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116 Citations

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Citation Type

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  • D. Berson
  • Biology
    Pflügers Archiv - European Journal of Physiology
  • 2007
TLDR
The overwhelming evidence that melanopsin serves as the photopigment in these cells is summarized and the emerging evidence that the downstream signaling cascade, including the light-gated channel, might resemble those found in rhabdomeric invertebrate photoreceptors is reviewed.
Vertebrate Bistable Pigment Parapinopsin: Implications for Emergence of Visual Signaling and Neofunctionalization of Non-visual Pigment
TLDR
A plausible link between the diversification of a non-visual opsin parapinopsin and diverse pineal functions, wavelength discrimination, and melatonin secretion, implying why multiple opsins exist in animals, is proposed.
Phototransduction in Rods and Cones
Vision: Under the spotlight
  • J. Qiu
  • Biology
    Nature Reviews Neuroscience
  • 2006
TLDR
The molecular machinery that underlies these pathways of light detection in the parietal eye is revealed, and it is suggested that the third eye is more primitive, and that imageforming lateral eyes might have evolved from their parietal ancestor but inherited only one G-protein pathway.
Jellyfish vision starts with cAMP signaling mediated by opsin-Gs cascade
TLDR
It is shown that the opsin-based pigment functions as a green-sensitive visual pigment and triggers the Gs-type G protein-mediated phototransduction cascade in the ciliary-type visual cells of the box jellyfish lens eyes, which implies a monophyletic origin of ciliary phototranduction cascades distributed from prebilaterian to vertebrate.
Evolution of opsins and phototransduction
TLDR
This work discusses the evolution of the counterion, the reduction of agonist binding to the receptor, and the molecular properties that characterize rod opsins apart from cone opsins, and shows how the advances in molecular biology and biophysics have given insights into how evolution works at the molecular level.
Phototransduction Motifs and Variations
Molecular and functional identification of a novel photopigment in Pecten ciliary photoreceptors
TLDR
Results establish this novel putative opsin as a bona fide visual pigment that couples to Go to convey the light signal.
Molecular Aspects of Evolution and Diversity of Animal Photoreception
TLDR
The visual transduction process in vertebrate and invertebrate photoreceptor cells, and the functional diversity of opsins and phototransduction systems in various photorecept cells are reviewed; the molecular mechanisms underlying the evolution and diversity of Opsins are discussed.
Photochemical nature of parietopsin.
TLDR
The mutational analysis revealed that parietopsin behaves as an "evolutionary intermediate" between invertebrate and vertebrate visual opsins.
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References

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