Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications
@article{Su2006ParietalEyePC, title={Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications}, author={C Y Su and Dong Gen Luo and Akihisa Terakita and Yoshinori Shichida and Hsi Wen Liao and Manija A. Kazmi and Thomas P. Sakmar and King-Wai Yau}, journal={Science}, year={2006}, volume={311}, pages={1617 - 1621} }
The parietal-eye photoreceptor is unique because it has two antagonistic light signaling pathways in the same cell—a hyperpolarizing pathway maximally sensitive to blue light and a depolarizing pathway maximally sensitive to green light. Here, we report the molecular components of these two pathways. We found two opsins in the same cell: the blue-sensitive pinopsin and a previously unidentified green-sensitive opsin, which we name parietopsin. Signaling components included gustducin-α and Gαo…
116 Citations
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