Parenteral polymyxin B use in patients with multidrug-resistant gram-negative bacteremia and urinary tract infections: a retrospective case series.

@article{Pastewski2008ParenteralPB,
  title={Parenteral polymyxin B use in patients with multidrug-resistant gram-negative bacteremia and urinary tract infections: a retrospective case series.},
  author={Andrew A Pastewski and Patricia Caruso and Addison R. Parris and Ramon Dizon and Robert Kopec and Shobha Sharma and Suri Mayer and Monica Ghitan and Edward K. Chapnick},
  journal={The Annals of pharmacotherapy},
  year={2008},
  volume={42 9},
  pages={
          1177-87
        }
}
BACKGROUND Parenteral polymyxin use declined after the 1960s, due to safety concerns. An increase in multidrug-resistant (MDR) gram-negative infections and a shortage of new agents have prompted increased use of parenteral polymyxin. OBJECTIVE To describe our clinical experience with parenteral polymyxin B for MDR gram-negative bacteremia and urinary tract infection (UTI). METHODS Paper pharmacy records were used to identify patients aged 18 years or older, presence of MDR gram-negative… CONTINUE READING

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Urinary tract infection.

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