Parenteral nutrition compromises neurodevelopment of preterm pigs.

  title={Parenteral nutrition compromises neurodevelopment of preterm pigs.},
  author={Asim F. Choudhri and Helen J K Sable and Viktor V Chizhikov and Karyl K. Buddington and Randal K. Buddington},
  journal={The Journal of nutrition},
  volume={144 12},
BACKGROUND Despite advances in nutritional support and intensive care, preterm infants are at higher risk of compromised neurodevelopment. OBJECTIVE This study evaluated the contribution of total parenteral nutrition (PN) to compromised neurodevelopment after preterm birth. METHODS Preterm pigs were provided PN or enteral nutrition (EN) for 10 d. Neurodevelopment was assessed by observations of motor activity and evaluation of sensory/motor reflexes, brain weight, MRI, and cerebellar… CONTINUE READING
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