Parenteral diclofenac infusion significantly decreases brain-tissue oxygen tension in patients with poor-grade aneurysmal subarachnoid hemorrhage

@inproceedings{Schiefecker2013ParenteralDI,
  title={Parenteral diclofenac infusion significantly decreases brain-tissue oxygen tension in patients with poor-grade aneurysmal subarachnoid hemorrhage},
  author={Alois Josef Schiefecker and Bettina E Pfausler and Ronny Beer and Florian Sohm and Jan Sabo and Viktoria Knauseder and Marlene Fischer and Anelia Dietmann and Werner O. Hackl and C. Thom{\'e} and Erich Schmutzhard and Raimund Helbok},
  booktitle={Critical care},
  year={2013}
}
INTRODUCTION Diclofenac, a nonsteroidal antiinflammatory drug, is commonly used as antipyretic therapy in intensive care. The purpose of this study was to investigate the effects of parenteral diclofenac infusion on brain homeostasis, including brain-tissue oxygen tension (PbtO2) and brain metabolism after aneurysmal subarachnoid hemorrhage (aSAH). METHODS We conducted a prospective, observational study with retrospective analysis of 21 consecutive aSAH patients with multimodal… CONTINUE READING
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  • JA Frontera, J Claassen, +4 authors SA Mayer
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