Parenteral chloroquine for treating falciparum malaria.

  title={Parenteral chloroquine for treating falciparum malaria.},
  author={Nicholas J. White and George Watt and Yngve Bergqvist and E K Njelesani},
  journal={The Journal of infectious diseases},
  volume={155 2},
There is no information and therefore no consensus on how chloroquine should be administered to persons with severe malaria. Although widely considered dangerous, parenteral chloroquine is extensively used. We studied the acute disposition and toxicity of intravenous (iv), intramuscular (im), subcutaneous (sc), and oral chloroquine in 60 adult Zambian patients hospitalized with falciparum malaria. Plasma concentration profiles after parenteral administration were characterized by wide… CONTINUE READING

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