Parenteral administration of progestin Nestorone to lactating cynomolgus monkeys: an ideal hormonal contraceptive at lactation?

Abstract

Nestorone (NES) progestin is highly effective for contraception following parenteral administration, but ineffective after oral ingestion due to rapid first-pass metabolism. Thus, NES might be ideal for lactational contraception; possible NES in milk should be metabolized by the nursing infant. We evaluated the distribution of NES, its endocrine effects and… (More)

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Cite this paper

@article{Heikinheimo1999ParenteralAO, title={Parenteral administration of progestin Nestorone to lactating cynomolgus monkeys: an ideal hormonal contraceptive at lactation?}, author={Oskari Heikinheimo and Sirpa Ranta and Alfred J Moo-Young and Pekka L{\"a}hteenm{\"a}ki and Keith Gordon}, journal={Human reproduction}, year={1999}, volume={14 8}, pages={1993-7} }