Parenteral administration of L-arginine prevents fetal growth restriction in undernourished ewes.

@article{Lassala2010ParenteralAO,
  title={Parenteral administration of L-arginine prevents fetal growth restriction in undernourished ewes.},
  author={Arantzatzu Lassala and Fuller W Bazer and Timothy A. Cudd and Sujay Datta and Duane H. Keisler and Michael Carey Satterfield and Thomas E Spencer and Guoyao Wu},
  journal={The Journal of nutrition},
  year={2010},
  volume={140 7},
  pages={1242-8}
}
Intrauterine growth restriction (IUGR) is a major health problem worldwide that currently lacks an effective therapeutic solution. This study was conducted with an ovine IUGR model to test the hypothesis that parenteral administration of l-arginine (Arg) is effective in enhancing fetal growth. Beginning on d 28 of gestation, ewes were fed a diet providing 100% (control-fed) or 50% (underfed) of NRC-recommended nutrient requirements. Between d 60 of gestation and parturition, underfed ewes… CONTINUE READING