Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohort

@inproceedings{MacDonaldWallis2010ParentalSD,
  title={Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohort},
  author={Corrie MacDonald-Wallis and Jon H. Tobias and George Davey Smith and D. A. Lawlor},
  booktitle={Osteoporosis International},
  year={2010}
}
We investigated an intrauterine influence of maternal smoking during pregnancy on childhood bone mass. Daughters, but not sons, of mothers who smoked had higher bone mass at age 10 years. This appears to be due to familial factors related to parental smoking influencing increased offspring adiposity rather than a direct intrauterine effect. Neonatal studies have demonstrated an adverse relationship between maternal smoking in pregnancy and foetal bone mineral accrual. We aimed to investigate an… CONTINUE READING