Parental origin of chromosomes involved in the translocation t(9;22)

@article{Haas1992ParentalOO,
  title={Parental origin of chromosomes involved in the translocation t(9;22)},
  author={Oskar Arthur Haas and Anthi Argyriou-Tirita and Thomas Lion},
  journal={Nature},
  year={1992},
  volume={359},
  pages={414-416}
}
FUNCTIONALLY equivalent genetic material can be labelled by an epigenetic marking process and used differentially depending on whether its origin is maternal or paternal1. This phenomenon is known as genomic imprinting and is manifested at either the chromosomal or gene level. Genomic imprinting seems to play an important role in cancer predisposition syndromes2–5, and phenotypic consequences are evident in constitutional deletion syndromes and uniparental disomies1. Moreover, there seems to be… CONTINUE READING

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