Parental origin and cell stage of non‐disjunction of double trisomy in spontaneous abortion

  title={Parental origin and cell stage of non‐disjunction of double trisomy in spontaneous abortion},
  author={Qing Ying Li and S. Tsukishiro and Chiaki Nakagawa and M. Tanemura and M. Sugiura-Ogasawara and K. Suzumori and S. Sonta},
  journal={Congenital Anomalies},
ABSTRACT  Using polymorphic analysis of microsatellites, we investigated the parental origin and mechanism of double trisomies seen in cases of spontaneous abortion. We obtained chorionic villi from spontaneous abortions, and peripheral blood from females who experienced abortion and their spouses. Chromosomal analysis of 170 cases revealed four cases with double  trisomy.  The  karyotypes  of  these cases are 48,XX,+16,+22, 48,XXY,+18, 48,XX,+15,+21 and 48,XX,+2,+5. In the present study, the… Expand
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Prenatal Diagnosis of Double Aneuploidy, 48,XXY,+21, and Review of the Literature
  • C. Jeanty, C. Turner
  • Medicine
  • Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • 2009


Double trisomy in spontaneous abortions
Nondisjunction of human acrocentric chromosomes: studies of 432 trisomic fetuses and liveborns
Double non-disjunction in maternal meiosis II giving rise to a fetus with 48,XXX,+21.
Cytogenetic analysis of 1508 spontaneous abortions originating from south Slovakia.
A cytogenetic study of 1000 spontaneous abortions