Parental age, genetic mutation, and cerebral palsy.

  title={Parental age, genetic mutation, and cerebral palsy.},
  author={Nicholas A. Fletcher and J. D. Foley},
  journal={Journal of medical genetics},
  volume={30 1},
Parental age and birth order were studied in 251 patients with cerebral palsy. No parental age or birth order effects were observed in spastic quadriplegia or diplegia, but a paternal age effect was detected in those with athetoid/dystonic cerebral palsy and congenital hemiplegia. These observations indicate that some cases of athetoid/dystonic or hemiplegic cerebral palsy might arise by fresh dominant genetic mutation.