Paraxial mesoderm specifies zebrafish primary motoneuron subtype identity.

@article{Lewis2004ParaxialMS,
  title={Paraxial mesoderm specifies zebrafish primary motoneuron subtype identity.},
  author={Katharine E Lewis and Judith S Eisen},
  journal={Development},
  year={2004},
  volume={131 4},
  pages={891-902}
}
We provide the first analysis of how a segmentally reiterated pattern of neurons is specified along the anteroposterior axis of the vertebrate spinal cord by investigating how zebrafish primary motoneurons are patterned. Two identified primary motoneuron subtypes, MiP and CaP, occupy distinct locations within the ventral neural tube relative to overlying somites, express different genes and innervate different muscle territories. In all vertebrates examined so far, paraxial mesoderm-derived… CONTINUE READING