Paratransgenesis applied for control of tsetse transmitted sleeping sickness.

@article{Aksoy2008ParatransgenesisAF,
  title={Paratransgenesis applied for control of tsetse transmitted sleeping sickness.},
  author={Serap Aksoy and Brian L Weiss and Geoffrey M Attardo},
  journal={Advances in experimental medicine and biology},
  year={2008},
  volume={627},
  pages={35-48}
}
African trypanosomiasis (sleeping sickness) is a major cause of morbidity and mortality in Subsaharan Africa for human and animal health. In the absence of effective vaccines and efficacious drugs, vector control is an alternative intervention tool to break the disease cycle. This chapter describes the vectorial and symbiotic biology of tsetse with emphasis on the current knowledge on tsetse symbiont genomics and functional biology, and tsetse's trypanosome transmission capability. The ability… CONTINUE READING

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