Parathyroids, thyroid and development of hypertension in SHR.

  title={Parathyroids, thyroid and development of hypertension in SHR.},
  author={Ren{\'e} Schleiffer and Alain Berthelot and Fanny Pernot and Alexis Gairard},
  journal={Japanese circulation journal},
  volume={45 11},
Parathyroid glands play a significant role in the development of hypertension in spontaneously hypertensive rat (SHR), like in deoxycorticosterone acetate (DOCA) + NaCl model. Parathyroidectomy (PTX) performed after weaning delayed systolic blood pressure (SBP) increase and slowed heart rate (HR) in SHR for 42 weeks. These changes could not be attributed to decrease of serum calcium in PTX animals since supplementation of calcium, rendering serum calcium normal, did not reestablish SBP and HR… CONTINUE READING

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