Parathyroidectomy reduces 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the hypocalcemic vitamin D-deficient chick.

@article{Booth1977ParathyroidectomyR2,
  title={Parathyroidectomy reduces 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the hypocalcemic vitamin D-deficient chick.},
  author={Branyan Booth and H C Tsai and Robert C. Morris},
  journal={The Journal of clinical investigation},
  year={1977},
  volume={60 6},
  pages={1314-20}
}
To test the hypothesis that in the vitamin D-deficient state the activity of 25-hydroxyvitamin D3-1 alpha-hydroxylase (25-OHD3-1 alpha-hydroxylase) is modulated by parathyroid hormone and the plasma concentration of phosphate only in the presence of small amounts of 1,25-dihydroxyvitamin D3 (or some other metabolite of vitamin D), we measured the activity of this enzyme 24 h after parathyroidectomy (PTX) in frankly hypocalcemic, vitamin D-deficient chicks that were not supplemented with vitamin… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 15 references

In - fluence of dietary vitamin D 3 on the circulating concentration of its active metabolites in the chick and rat

  • L. A. Baxter, H. F. DeLuca
  • Endocrinology .
  • 1977

The role of 1 , 25 - dihydroxyvitamin D 3 and parathyroid hormone in the regulation of chick renal 25 - hydroxyvita - min D 3 - 24 - hydroxylase

  • L. Castillo, Y. Tanaka
  • Arch . Biochem . Biophys .
  • 1975

The story of vitamin D from vitamin to hormone

  • H. F. DeLuca, H. K. Schnoes
  • Lancet
  • 1974

The control of 25 - hydroxyvitamin D metabolism by inorganic phosphorus

  • E. G. Bligh
  • Arch . Biochem . Biophys .
  • 1973

Isolation and identification of 24 , 25 - dihydroxycholecalciferol , a metabolite of vitamin D 3 made in the kidney

  • C. H. Fiske, Y. Subbarow
  • Biochemistry .
  • 1972

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