Parathyroid hormone-related protein reduces alveolar epithelial cell proliferation during lung injury in rats.

@article{Hastings2000ParathyroidHP,
  title={Parathyroid hormone-related protein reduces alveolar epithelial cell proliferation during lung injury in rats.},
  author={Randolph H Hastings and J. W. M. Ter Berg and Daphne Summers-Torres and Douglas W. Burton and Leonard John Deftos},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2000},
  volume={279 1},
  pages={L194-200}
}
Parathyroid hormone-related protein (PTHrP) is a growth inhibitor for alveolar type II cells and could be a regulatory factor for alveolar epithelial cell proliferation after lung injury. We investigated lung PTHrP expression in rats exposed to 85% oxygen. Lung levels of PTHrP were significantly decreased between 4 and 8 days of hyperoxia, concurrent with… CONTINUE READING