Parathyroid hormone-related protein: roles in the glomerulus.

  title={Parathyroid hormone-related protein: roles in the glomerulus.},
  author={Ricardo Juan Bosch and Diego Rodr{\'i}guez-Puyol and Jordi Bover and Manuel Rodr{\'i}guez-Puyol},
  journal={Experimental nephrology},
  volume={7 3},
Parathyroid hormone (PTH) and PTH-related protein (PTHrP) produce similar biological effects through the PTH/PTHrP receptor. Less is known about the physiological role of PTHrP which was first identified as the agent of the humoral hypercalcemia of malignancy. Despite the widespread production of PTHrP in healthy individuals, the concentration of the protein is below the detectable limit of current assays, suggesting that PTHrP normally functions locally in an autocrine or paracrine manner… CONTINUE READING

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