Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis.

@article{Donahue2006ParathyroidHM,
  title={Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis.},
  author={Seth Donahue and Sarah A Galley and Michael R. Vaughan and Patricia Patterson-Buckendahl and Laurence M. Demers and J L Vance and Meghan E. McGee},
  journal={The Journal of experimental biology},
  year={2006},
  volume={209 Pt 9},
  pages={
          1630-8
        }
}
Mechanical unloading of bone causes an imbalance in bone formation and resorption leading to bone loss and increased fracture risk. Black bears (Ursus americanus) are inactive for up to six months during hibernation, yet bone mineral content and strength do not decrease with disuse or aging. To test whether hibernating bears have biological mechanisms to prevent disuse osteoporosis, we measured the serum concentrations of hormones and growth factors involved in bone metabolism and correlated… CONTINUE READING

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