Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet.

@article{Marks1997ParathyroidHG,
  title={Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet.},
  author={Keith H. Marks and Rachel Kilav and Emily Rose Berman and Tally Naveh-Many and Justin M Silver},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={1997},
  volume={12 8},
  pages={
          1581-5
        }
}
BACKGROUND The murine analogue of X-linked hypophosphataemia is the Hyp mouse; it has chronic phosphate depletion from an inherited defect of renal tubular reabsorption. Phosphate directly regulates the parathyroid (PT) in normal rats and it is of interest whether this regulation is intact in Hyp mice. METHODS Hyp mice were fed either a low-phosphate diet or control diet and PTH mRNA levels were measured. In addition changes in NMR-visible kidney and muscle intracellular phosphate potentials… CONTINUE READING
BETA