Parathyroid hormone and bisphosphonate have opposite effects on stress fracture repair.

@article{Sloan2010ParathyroidHA,
  title={Parathyroid hormone and bisphosphonate have opposite effects on stress fracture repair.},
  author={Ashley V Sloan and Joseph R. Martin and Shuo Li and Jiliang Li},
  journal={Bone},
  year={2010},
  volume={47 2},
  pages={235-40}
}
This study was aimed to investigate the effects of Parathyroid hormone (PTH) and alendronate (ALN) on stress fracture repair. Stress fractures were induced in the ulnae of female adult rats. Animals were treated daily with vehicle, PTH (40 microg/kg) or alendronate (2 microg/kg), respectively. Bone mineral content (BMC) and bone mineral density (BMD) of bilateral ulnae were measured at two, four and eight weeks following induction of stress fracture. Histology at the ulna midshaft was… CONTINUE READING