Parathyroid hormone (PTH)-related protein(1-36) is equipotent to PTH(1-34) in humans.

  title={Parathyroid hormone (PTH)-related protein(1-36) is equipotent to PTH(1-34) in humans.},
  author={M Everhart-Caye and Silvio E. Inzucchi and J Guinness-Henry and Mary Ann Mitnick and Andrew Francis Stewart},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={81 1},
Humoral hypercalcemia of malignancy (HHM) results from the production of PTH-related protein (PTHrP) by human tumors. One previous study has reported the results of human (h) PTHrP(1-34) infusion into humans. In that report, hPTHrP(1-34) was found to be qualitatively similar to but 3- to 10-fold less potent than hPTH(1-34). Because hPTHrP(1-36) and not hPTH(1-34) is likely to be the actual amino-terminal secretory form of PTHrP, and because this previously reported lack of potency was… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 45 references

Similar Papers

Loading similar papers…