Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction.

@article{Vaseghi2017ParasympatheticDA,
  title={Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction.},
  author={Marmar Vaseghi and Siamak Salavatian and Pradeep S. Rajendran and Daigo Yagishita and William R. Woodward and David W Hamon and Kentaro Yamakawa and Tadanobu Irie and Beth A Habecker and Kalyanam Shivkumar},
  journal={JCI insight},
  year={2017},
  volume={2 16}
}
Myocardial infarction causes sympathetic activation and parasympathetic dysfunction, which increase risk of sudden death due to ventricular arrhythmias. Mechanisms underlying parasympathetic dysfunction are unclear. The aim of this study was to delineate consequences of myocardial infarction on parasympathetic myocardial neurotransmitter levels and the function of parasympathetic cardiac ganglia neurons, and to assess electrophysiological effects of vagal nerve stimulation on ventricular… CONTINUE READING