Parasympathetic activation by pyridostigmine on chemoreflex sensitivity in heart-failure rats

Abstract

We evaluated the effects of parasympathetic activation by pyridostigmine (PYR) on chemoreflex sensitivity in a rat model of heart failure (HF rats). HF rats demonstrated higher pulmonary ventilation (PV), which was not affected by PYR. When HF and control rats treated or untreated with PYR were exposed to 15% O2, all groups exhibited prompt increases in… (More)
DOI: 10.1016/j.autneu.2013.07.001

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