Parasitism as the main factor shaping peptide vocabularies in current organisms.

@article{Zemkov2017ParasitismAT,
  title={Parasitism as the main factor shaping peptide vocabularies in current organisms.},
  author={Michaela Zemkov{\'a} and Daniel Zahradn{\'i}k and Martin Mokrejs and Jaroslav Flegr},
  journal={Parasitology},
  year={2017},
  volume={144 7},
  pages={
          975-983
        }
}
  • Michaela Zemková, Daniel Zahradník, +1 author Jaroslav Flegr
  • Published 2017
  • Biology, Medicine
  • Parasitology
  • Self/non-self-discrimination by vertebrate immune systems is based on the recognition of the presence of peptides in proteins of a parasite that are not contained in the proteins of a host. Therefore, a reduction of the number of 'words' in its own peptide vocabulary could be an efficient evolutionary strategy of parasites for escaping recognition. Here, we compared peptide vocabularies of 30 endoparasitic and 17 free-living unicellular organisms and also eight multicellular parasitic and 16… CONTINUE READING
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